Optometry Research Today is a free monthly online journal that collates and summarizes the latest research about Optometry, including details on myopia, optometric practice, therapy.

Diagnosis and management of Thygeson's superficial punctate keratitis.

Duszak RS

Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania 19104, USA. bduszak@mac.com

BACKGROUND: Thygeson's superficial punctate keratitis (TSPK) is a chronic disease with exacerbations and remissions over years to decades. Hallmarks of the disease include multiple, whitish-gray, intraepithelial corneal lesions with minimal or no conjunctival involvement. Although its exact etiology is controversial, TSPK has a genetic association with HLA-DR3, an antigen associated with immunogenic responses. Treatment of the disease varies depending on severity and can consist of artificial tears, corticosteroids, topical cyclosporine, or soft contact lenses. CASE REPORT: A 33-year-old African-American man presented with a complaint of a foreign body sensation in both eyes. After a thorough examination, a diagnosis of TSPK was made, and after appropriate management, complete resolution of the acute disease ensued. CONCLUSIONS: A discussion of the case presented aims to provide clinicians with a clearer understanding of the clinical findings, etiology, and management of TSPK.

Published 2 July 2007 in Optometry, 78(7): 333-8.
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