Optometry Research Today is a free monthly online journal that collates and summarizes the latest research about Optometry, including details on myopia, optometric practice, therapy.

Evaluation of the Xal-Ease(trade mark) latanoprost delivery system.

Semes L, Shaikh AS

University of Alabama, Birmingham Optometry, Birmingham, Alabama.

PURPOSE: The purpose of this study was to compare drops of latanoprost dispensed using the Xal-Easetrade mark (Pfizer Ophthalmics, New York, New York) delivery system with drops dispensed manually. METHODS: Twenty-four 2.5-mL bottles of Xalatan(R) (Pfizer Ophthalmics) were evaluated with or without the delivery system. Individually dispensed drops were counted. The total volume dispensed was measured to the nearest 10 muL. Statistical analysis compared group means by analysis of variance. P values less than 0.05 were considered significant. RESULTS: The overall mean volume was 2,850 muL. Overall mean drops per bottle (n = 24) were 90.3 +/- 6.3. Using the Xal-Ease, mean drops per bottle were 93.0 +/- 3.4 and without it, 87.7 +/- 7.5 (n = 12 each). CONCLUSIONS: With Xal-Ease, mean drops per bottle (5) were statistically significantly greater when compared with standard dispensing (P = 0.0393). This result is accounted for by more consistent individual drop volume and greater volume using the delivery system.

Published 8 January 2007 in Optometry, 78(1): 30-3.
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